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Gastroesophageal Reflux in Infants

Gastroesophageal Reflux in Infants

- A common phenomenon in the first months of life -

Refluxul gastroesofagian in infants is characterized by the passage of stomach contents into the esophagus, causing local irritation and feeding discomfort. It is common in infants under 12 months, due to immaturity of the lower esophageal sphincter.

How does it manifest itself? 

Symptoms may include:
  • frequent regurgitation
  • vomiting after meals
  • iritabilitate
  • prolonged crying
  • sleep disorders
  • feeding difficulties
Infants may sometimes present with burning sensations or a cough associated with reflux.

Causes and Mechanism

The mechanism involves an immature lower esophageal sphincter, horizontal positioning, and increased gastric pressure. Gastric acid irritates the esophageal mucosa and can cause mild inflammation or discomfort.

Therapeutic solutions

Compounded preparations help protect the mucosa and reduce symptoms:
  • mucoprotective and antacid agents: hidroxid de aluminiu, alginat
  • bases adapted for oral administration in infants, free of preservatives or irritating excipients
  • proton pump inhibitors to reduce gastric acidity: omeprazol, esomeprazol
These formulations can be customized for dose and consistency, increasing tolerance and effectiveness.
You can check out some examples of recommended compounded treatments here
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